Montelukast as add-on therapy with inhaled corticosteroids or inhaled corticosteroids and long- acting beta-2-agonists in the management of patients diagnosed with asthma and concurrent allergic rhinitis (the RADAR trial)
نویسندگان
چکیده
1McMaster University, Hamilton, Ontario; 2Merck Frosst Canada Ltd, Montreal; 3Université Laval, Quebec; 4McGill University, Montreal; 5JSS Medical Research, Montreal, Quebec; 6University of British Columbia, Vancouver, British Columbia Correspondence: Dr PK Keith, McMaster University, 1200 Main Street West, 3V7-Health Sciences Centre, Hamilton, Ontario L8N 3Z5. Telephone 905-521-2100 ext 76374, fax 905-521-4971, e-mail [email protected] AsthMA cARe in cAnADA
منابع مشابه
Inhaled salmeterol/fluticasone propionate: a review of its use in asthma.
Salmeterol/fluticasone propionate, administered twice daily via a multidose dry powder inhaler (Seretide/Advair Diskus), Seretide Accuhaler or metered-dose hydrofluoroalkane (chlorofluorocarbon-free) inhaler (Seretide Evohaler), is a combination of the long-acting beta(2)-adrenoceptor agonist (beta(2)-agonist) [LABA] salmeterol and the corticosteroid fluticasone propionate. Maintenance therapy ...
متن کاملLong-acting beta-agonists with and without inhaled corticosteroids and catastrophic asthma events.
BACKGROUND It is unclear whether long-acting beta-agonists with concomitant inhaled corticosteroids increase asthma-related intubations and deaths. We pooled data on long-acting beta-agonists with variable and concomitant inhaled corticosteroids to evaluate the risk for catastrophic asthma events. METHODS We conducted searches of electronic databases, the US Food and Drug Administration websi...
متن کاملMontelukast in pediatric asthma management.
UNLABELLED Leukotriene modifiers (receptor antagonist and biosynthesis inhibitor) represent the first mediator specific therapeutic option for asthma. Montelukast, a leukotriene receptor antagonist is the only such agent approved for use in pediatric patients. Montelukast modifies action of leukotrienes, which are the most potent bronchoconstrictors, by blocking Cysteinyl leukotriene receptors....
متن کاملEvidence-based asthma management.
In 2002 the National Asthma Education and Prevention Program published evidence-based guidelines for the diagnosis and management of asthma, but there are some unresolved asthma-management issues that need further research. For asthmatic children inhaled corticosteroids are more beneficial than as-needed use of beta(2) agonists, long-acting beta(2) agonists, theophylline, cromolyn sodium, nedoc...
متن کاملاثر سلولهای بنیادی مزانشیمی مغز استخوان بر آسم آلرژیک در مدل موش
Background: Allergic Asthma is an inflammatory disease of the respiratory system that is well known by increased inflammatory cells in the airways and causes difficulty in respiration. The prevalence of allergic asthma is increasing worldwide, and it has become a significant cause of health challenge especially in developed countries. Inhaled β2-agonists and Inhaled or oral corticosteroids are ...
متن کامل